Description
Product Characteristics: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.
Target Information: non-selective cation channel\, activated down-stream of G-protein-coupled receptors [RGD, Feb 2006]